Granular Cell Tumour: A Clinicopathological Study with Review of Literature
Published: September 1, 2018 | DOI: https://doi.org/10.7860/JCDR/2018/36320.12004
Geetha Vasudevan, Padmapriya Jaiprakash
1. Additional Professor, Department of Pathology, Kasturba Medical College, Manipal, Manipal Academy of Higher Education, Karnataka, India.
2. Associate Professor, Department of Pathology, Kasturba Medical College, Manipal, Manipal Academy of Higher Education, Karnataka, India.
Correspondence
Dr. Padmapriya Jaiprakash,
Associate Professor, Department of Pathology, Kasturba Medical College, Manipal, Manipal Academy of Higher Education,
Karnataka-576104, India.
E-mail: padmapriya.j@gmail.com
Introduction: Granular Cell Tumours (GCTs) can occur in any part of the body. Many a times, they occur as a small swelling, clinically suspected to be a benign process. Histologically, they are characterised by the presence of cells with abundant granular cytoplasm.
Aim: To study the clinicopathological spectrum of GCTs diagnosed.
Materials and Methods: Data were collected from the archives of the Department of Pathology, on diagnosed cases of GCTs for a period of five years; from 2012 to 2017 and a total of 22 cases were included in the study. The slides, including special stains and Immunohistochemistry (IHC), whenever performed, were retrieved and studied. The results were tabulated and analysed.
Results: In the present study 22 cases of GCT were described, commonly involving skin and subcutaneous tissue. Most of the lesions were less than a centimeter in size. Females were more often affected. On follow-up, no recurrence was noted.
Conclusion: Granular cell tumours should be a part of the diagnostic differentials whenever lesions with granular cells are encountered.
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